pentobarbital will reduce the extent or effect of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.pentobarbital will lessen the extent or effect of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic impact of elbasvir/grazoprevir may be l